BTC Media was founded in 2013 by David Bailey and Tyler Evans. The company initially leveraged the Bailey family’s expertise in print publications to launch yBitcoin, one of the earliest industry publications with global distribution.  Shortly after, BTC Media purchased Bitcoin Magazine from Vitalik Buterin and acquired the Let's Talk Bitcoin podcast network. As the broader cryptocurrency industry explored blockchain technology, the company launched new products such as the Distributed conference series and publication to cover these emerging trends. BTC Media expanded rapidly, hosting quarterly conferences and launching new technology and media products.

In the fallout of the Bitcoin Block Size Wars, and disillusioned by the shortcomings of the blockchain technology trend, BTC Media rebranded as BTC Inc with a singular mission:  to go all in on a Bitcoin-only strategy. In the midst of the bear market, Bailey published the seminal blog post Make Bitcoin Fun Again, and the company relaunched the annual Bitcoin Conference. Hosted in a warehouse in San Francisco, Bitcoin 2019 became a watershed moment for a fractured Bitcoin industry. The event rekindled a mainstream interest in Bitcoin and brought together top leaders of the industry for the first time in years. Weeks before Bitcoin 2020 was set to take place, global COVID-19 lockdowns brought the events industry to a standstill, forcing BTC Inc to weather the storm.

During this period, BTC Inc reset to a focused core team to carry the company forward through uncertainty. In response to global lockdowns, the team launched the Bitcoin-earning app Carrot and introduced new leadership at Bitcoin Magazine as the brand expanded its product lineup and relaunched its print edition. In 2021, The Bitcoin Conference moved to Miami and hosted Bitcoin 2021. The event drove some of the largest announcements in bitcoin to date and pushed mainstream interest in bitcoin to new highs. Building on that momentum, Bitcoin 2022 introduced Sound Money Fest and became the largest Bitcoin conference ever, with more than 37,000 attendees.. The conference continued to thrive throughout the 2023 bear market and expanded internationally, beginning with Bitcoin Amsterdam in 2022. Since then, The Bitcoin Conference has grown into a global event series with annual conferences in Hong Kong and Abu Dhabi, while the flagship U.S. event reached new heights — culminating in President Trump delivering the keynote at Bitcoin 2024 in Nashville.